Great trip and well worth doing in our opinion. We took about 4 days to go each direction and spent about 3 days in Inuvik. We made lots of stops along the way and took our time. You will encounter all kinds of conditions as mentioned above as well as the possibility of forest fires and resulting smoke.
There is (assume it is still there) a v.g. car wash in town and it is recommended you clean your RV when you arrive. Do it again when you reach Dawson.
There are now bridges across the rivers and it is no longer necessary to take a ferry. The road from Inuvik to Tuk will also be open this summer. That would be another adventure and one that not many have done yet. Flying was the only way to get to the Arctic Ocean, but now you can drive! You will see every type of RV on the road. Truck campers are the most suited though.
Note that Pigman1 above is talking about the Alaska road to the Arctic, not the Dempster highway in Yukon.