As a resident of Reno I have traveled I80 all times of the year, including crossing Donner Pass in winter towing. Unless you are fixed on a date/time crunch I would suggest watching the weather reports and travel accordingly. If you get to Reno and the roads are bad just stay over until they clear up, and there are plenty of RV parks to stay at while the roads clear up. You will hit a couple of passes getting here but nothing long until you get into California. Unless you are traveling in an extended stormy period the pass is usually not difficult and the roads are often dry. Just in case, I always carry tire chains for both my pickup and trailer as I really don't want to get caught without them.
Willcamp4
2012 Ford F-250 Super Duty, Crew Cab, Lariat, 6.7L PSTD, Air Lift rear suspension.
Alpenlite Valhalla Limited Fifth Wheel, two Solar panels, four six-volt batteries, two Honda EU2000i generators