I vastly prefer US-90 from San Antonio to Van Horn over taking I-10.
It is only a few miles farther. Has some great stops like Seminole Canyon SP, Judge Roy Bean Museum in Langtry, Marathon, Alpine, Marfa. Only a short (Texas definition of short) bit off the route to Big Bend National Park and/or Davis Mountains SP and the MacDonald Observatory and Fort Davis National Monument.
If you've never been Garner SP north of Uvalde is a great first stop on the trip.
Getting past El Paso. I've stayed at the Fort Bliss RV Park, but other than that, I do not like to stop for the night between Van Horn and Las Cruces.
In NM Rockhound SP and City of Rocks SP, both near Deming are worth a visit b