It is the way we usually go to the coast, and I believe I've tried every different route at least once (hwy 36 I tried WITHOUT the trailer, of course).
There is construction along the route. They've run news stories and updates on the Redding TV station. It is a well maintained road and you will have no problems. The scenery is ok. The grades are steep but there are usually extra lanes.
Once you reach hwy 101, the scenery is excellent! Don't miss Fern Canyon by Orick, if you can make it. Your trailer will NOT be allowed on that 5 or 6 mile drive to get there, but it's worth it IMHO, if you can stash the trailer or leave it at a nearby campsite.
The only other acceptable routes with a trailer would be Hwy 20 from Williams to 101, and hwy 199 from Grants Pass to 101.
Phil
'03 F250 7.3 deezle and '01 Komfort 27FS
Off the grid and outta sight at home
Go camping to have neighbors and amenities