I 70WB from Cambridge to Columbus in Ohio is in good shape. Construction in Downtown Columbus can create tie ups. Try to avoid the Columbus Area going westbound during the AM rush hours 6:30–>9AM weekdays. In the afternoon try to be west of Columbus before 3:30PM. as traffic can get really congested headed into/out of downtown. Especially if there is any rain AT ALL or other accidents. OHGO.com is a good resource.
Edit: On a Saturday you should good for the above mentioned part of I70W except possible delays in downtown Columbus due to reconstruction of the 70/71 “Split”. Can’t help you father west than DT Cbus. Have a great trip!