We've run the Trace and it's a great run. We've run it in a 43' diesel pusher pulling a full size pickup and there are a few cautions. Although the Trace has a number of pull off's with various historical significance, you cannot get into AND OUT OF all of them with a big rig. All tight ones are marked, but the signs are carved wood, small and low on the grass. Watch CLOSELY for them. Another issue is overhanging branches. The Trace is only 2 lanes WITH ABSOLUTELY NO SHOULDERS. In some areas they do not keep tree branches cut back far enough and staying in your lane may get you a fair share of scratches and an occasional hard bump. Just be careful. Collect some travel guides and have the copilot keeping up with your travels. Makes for a much better experience. Finally, although the "rules" tell you you are not allowed to overnight at the many turnouts, we have done it repeatedly. We didn't put out awnings, BBQ's, lawn chairs and such but we saw numerous rangers pass us without a second look. It's a great run. ENJOY.