I have three routes to choose from: 1) I-40 to I-30 to I-20 to I-10, 2) I-85 to Atlanta then I-20 to I-10, I-85 to I-65 to I-10. Routes #1 I have to go through Chattanooga, Knoxville, Nashville, Memp...
We have not used I-20 across Mississippi and Louisiana for a couple of years now, but it used to be really rough on the trailer. Profile like ocean waves and that set up a harmonic bouncing that was really bad. Then you would hit a bad pavement joint that would knock your teeth loose.
We now stay on 10 until West of Slidel and cut up through Alexandria to the Texas border.
From NC you don't want to drop that far South, but you might want to see what you can come up with to avoid that stretch.