From Lakeview take 33 into Columbus and get on 270 then hop on 23 down to Chillicothe where you will hop on 35 till you hit 64. Take 64 to 81 and you are there.... a couple things to note. 64/77 is a toll road for much of the way. 33,23, and 35 are all RV friendly state routes. I've been on them many times. Make sure to go to Shenandoah NP while you are in Staunton. There are some hills but nothing terrible in WV. Heading up 81 you'll be in a valley. There isn't much to speak of as far as gas stations go on the section of 64 that heads straight east once you make the turn in Beckley.