Route 501 in Virginia, Lynchburg to I-81

Thanks all. I'm traveling north so I'll take the 29 north route.

Concur with KD4UPL. North on I-81, take US-29 North to I-64 West, cross Afton Mountain, and then turn north on I-81.

Going south from Lynchburg, take US 460 West to US-220 Alternate which takes you over to I-81 South.

I traveled 501 with my truck camper. No problems but it kind of windy in places. Big rigs run it so of course it can be done. With a 38' MH I probalby wouldn't since there are better options. If going north on I81 I would take 29N to I64. If going south on I81 I would take 460 west.

It depends on which direction you are going on 81. If I was going south, take 460 west to Blueridge and cut across to 81 there.

501 is a two lane with a lot of log trucks working the area. Drove it Tuesday, with a car, no Construction, Big island area is a very steep and twisty stretch. Semi's travel it, but they are slooow.

drove 29 from Lynchburg to Charlottesville also, one patch of construction, but moved well.

Dont know if this will work but this should be a link to the section just east of Big Island.
501 east of big island

29 north to 64 is a sure route. I have gone 460 as well and it is good.