Straight down 99 to 210 and travel east to San Bernardino. Pick up Interstate 10 and head east from there. Only snow issue would be the Grapevine but you'll be escorted through there if a freak snowstorm shows up. May should be good traveling weather. Not too much to see until you get out of California. Assuming a full tank of fuel you won't have to fill up again until you're in Arizona. Go thru Blythe and fill up at the Chevron off Tom Wells road, about 5 miles east of Blythe. Better prices-currently $2.93 for diesel. East on 10 will take you to Phoenix. You can bypass Phoenix by taking Loop 202 toward South Mountain. It's open now. 202 will take you back to 10 near Wild Horse. WH may be a stop depending on what is going on in May. Casino, race track, small city. Interesting place. Continue down 10 to Tucson. Tons of stuff to do in Tucson. If you plan a layover that's the place I'd do it. I can give you some 'stuff' to see if you ask. From there stay on 10 east. Not much to see until you get to Texas and even then there's a lot of desert to get thru. Build a better itinerary and I can help you with campgrounds. We travel 250-300 miles/day when moving but usually stay put for 4-5 days once arriving. Gives us time to explore. The area around Fredricksburg Texas is interesting and there are State Parks for bunking down. Stay along the Gulf the rest of the way and the weather should be a non factor. Build your itinerary around this route and come back with some timelines for better advice....Dennis