through nyc ?

Several things to consider with only one real issue, are you well seasoned at pulling a trailer in difficult situations, because the area that you'll be trying to navigate with a combination vehicle can be the most difficult in the nation. Going where the unsure can have issues. As suggested you can use the round about much safer, much longer I 81 or the Tappanzee 287 in Jersey and toll roads south I 95 shorter but congested route which can be a white knuckler for the timid. Or consider using the jersey route/287 and work your way down to Virginia Beach using 13 through Delaware.