US 219 Dubois, Pa to Buffalo NY

[Zany]

Planning to drive from I80 near Dubois Pa on US 219 to Buffalo NY. Anyone know of any issues or conditions along that route that would affect driving a 40' coach with toad?
Any recommendations for getting around Buffalo? I want to get to I 190 and then Youngstown NY?
I'll appreciate any response

[mbopp]

The town of Limestone (just over the NY line) has been a speed trap for years. Not that you can do much over 40MPH with the rough road though. Other than that your're OK IIRR.

[Richert]

It's a scenic drive, don't be in a hurry. No problems on that route.