OK, here is just one example:
First day drive to Sevierville/Gatlinburg, TN 240 miles, easy drive
East at the Apple Tree Restaurant -- Dinner arrival day, or lunch the next day.
Second day drive to Kentucky Horse Park north of Lexington
visit Lexington as well as the Horse Park
Third day drive to Archbald, Ohio and stay at Sauder Village RV Park
Eat as Amish restaurant Visit the village
Fourth day drive to Holland, MI only 175 miles, arrive rested.
We have stayed in all the places. Several different campground in the Sevierville area. Riverside is good.
Horse Park includes a fine campground. Be sure to reserve.
We have stayed at Sauder RV Park several times.
If 250 miles is too short a day, I can give you an entirely different 3 day trip.