We leave Ohio in January for Florida also... and pretty much do as everyone mentioned above, however we do use our 5th Wheel the entire trip. We watch the weather close before leaving to not run in snow or ice. We put a full day of driving the 1st day. We like above bring water with us for brushing teeth and coffee. We normally spend the night at a Flying J, which has RV designated parking areas. We heat with our propane furnace and sleep in the 5th Wheel. In the morning if temperatures are above 30, we will un-winterize that morning at the Flying J... they have freshwater, sewer dump and propane right there. Our 2nd night is normally fine temperature-wise... We have been doing this for over 20 years.
RVman / John