In '78 I drove up Highway 1 from Morro Bay to Fort Bragg in a 1976 Buick. I have wondered if I could do it again towing my 30' 5'ver. That part of the Highway is in two parts. From Morro Bay to the...
While there is no good route through SF 19th Ave is much better than 101. Stay in the middle lane when available and avoid rush hour traffic. North bound is the free bridge direction. I've taken this route in both directions many times but it's city driving.
You can also take Skyline Blvd and then Geary. You cannot turn left on US 1 so loop to the right.