We have a B+ and travel with our cat. It is a challenge at times, but mostly a good experience for us. Maybe not so much for the cat ;-).
She has escaped once and almost one other time. My wife was very resourceful and finally captured her. We always watch for the cat when getting in the front doors and created a folding plywood barrier for the side door so we can get in, close the door and remove the barrier.
All cats are different. Ours walks on a lease and will tolerate living and traveling in a small space. We try to get her out on the lease at least once a day.
We learned how to deal with her...how to make it work with this specific cat. That said, it would be a lot easier to travel without a cat ;-).