Although I've never personally owned a 460, I have two friends that have.
They seemed to have two primary issues.
First, fuel economy, or lack thereof. Apparently the 460's love that gas, and 6 mpg was not uncommon for either of them.
Secondly was noise due to high RPM's at interstate speeds. At 70 mph the engine is quite noisy, and it's going through fuel like there's no tomorrow.
A newer V-10 version is what both of them ultimately bought, and both seem to be happy with their decision.
. . . never confuse education with intelligence, nor motion with progress