Check seals at least twice a year. Do something about anything that doesn't look right. Better to reseal something that doesn't need it, than to chase after something that's already a problem.
The only leak I ever had was on my old hybrid when it was about 7 years old. A seal on the roof where it meets the front crown dried up. I removed the Dicor, peeled the crown panel back, dried out the wet areas, resealed with Eternabond. No serious damage.
In the case of more serious damage you may have to remove cabinets and other components.
Wet wood will start to rot after a few weeks. It's a slow process though and more often than not if you catch it you can save it. I don't know how long it takes vacu-bonded walls to delaminate.