Another advantage of a motor home is that if you give up the toad, you can pull another decent sized trailer instead. That's what made the decision for my wife and I - a TT or 5er would have been cheaper, and we already have a decent truck, but we wanted to be able to go camping with our horses.
Essentially, the motor home enables you to take your other hobbies with you, whether it's a boat, horse trailer, snowmobile trailer, etc. Sure you can get a toy hauler or a triple-towing setup, but those solutions aren't ever going to be as flexible.