My Goodyear G614 G rated tires are designated LT235/85R16 but are sold for "Even Wear In Demanding Trailer Applications". They are also rated for 75 mph.
I think the real problem in most tire situations is age and/or LOAD. Tires on trailers come low bid and low spec...barely sufficient and then we overload them, or the weight transfer of traveling places a transient load that is above spec and the cheap, low spec tire just can't take it.
I don't think we can point to any one thing or magic bullet or set of letters on a tire...