Let 12V battery drop to 50 pct, or top it off daily?

I keep my meds tucked away under the bed, away from heat sources like fridge and microwave. They stay cool there even when the rest of the rig is hot.

Mex (and others), is it really best to NEVER deeply cycle batteries? Like, over years?

I had the impression that it was better for them to get down to 12ish at least once in a while -- with a 100% recharge right after -- and that only using the top 5% caused a loss of capacity over time.