I would leave the wires to the bedroom speakers in place. For resale or addition of a screen in the bedroom, you'll still have functionality of those speakers. Pulling wire in an RV is sometimes difficult through wall and ceiling spaces. It may be necessary to pull through the floor and up through wall to place the locations. Alternatives to the placing of wire inside walls and ceilings are to surface mount or use wireless speakers. Additionally, boxed speakers can be used and hung from cabinets or walls.
What I did was use boxed speakers in two locations, front and back. I use a stereo receiver that has two speaker section outputs so can turn each off if I desire. I could have installed a 5.1 or 7.1 system but my reasoning was this: The space that I need to fill when using a screen or just sound is small and highly reverberant. At best, tuning the sound to just one seating location was the best that could be hoped for and if using 5.1 results would not be spectacular unless using sound absorption and traps. As it is, the four speakers offer up the necessary coverage for my listening needs. In fact, just using two fronts is usually good enough. YMMV, and a lot of this depends on how you perceive sound, It can be done but is a lot of work for, IMO, less than stellar results.