Yeah but in the '60s, trucks were designed with a drafting board and a slide rule.
Today they are CAD designed with extensive computer simulation testing done on the structure before they even go to prototype stage. Much more sophisticated. Weak points are easily predicted and identified.
There would be no TECHNICAL reason that a unibody pickup could not be designed to be just as strong as a body-on-frame. If not stronger.
It's just people's old-fashioned proclivities that if it's unibody, it can't possibly be any good now because they weren't any good in the 1960s.
Ford will never try a unibody F150 because they know the frankly ignorant buying public would reject it outright without even giving it a chance.
Putting 10-ply tires on half ton trucks since aught-four.