I would not have an issue pulling a 4K trailer with a current 4.3V6 and a 6 sp. That has more HP than my 5.7 Vortec V8 at 255 and 335 lb ft of torque. I have a lot tall geared rig despite 4.10 gears in the axel. I only have a 2.48 first gear, the 4.3 will have a 4.1 first gear and a 3.42 axel, or should have a 3.42 axel.
I've actually been toying with trading my 2000 C2500 on a new 1500 with a 7200 gvwr pkg if I could find one in a reg cab as I have, might lose 1000 lbs max of total payload, registered gvwr in Wa st will be 8K gvw as is my C2500, so no real loss there. Both will weigh in at about 4800 lbs empty. Towing upwards of 8K lbs of low frontal area rigs, ie bobcat, small trackhoe etc on an equipment trailer........WHat is not to like about the new rig frankly.
If the trailer is reasonably aerodynamic, should pull fine getting low double digits, ie 10-12 mpg towing, and low to mid 20s on the freeway, around 18 in town. That is what my older 4.3's got with less than 200hp doing what I just described, along with the 4 sp auto to boot, which is not as good as the newer 6 sp!
Marty
92 Navistar dump truck, 7.3L 7 sp, 4.33 gears with a Detroit no spin
2014 Chevy 1500 Dual cab 4x4
92 Red-e-haul 12K equipment trailer