This past February marked our 20-year anniversary of truck camping. The span of years has included two truck campers and two F350's. We added air bags to the first truck, but have been running our 2012 6.7 s/b stock. Both set-ups handled amazingly well - especially our current truck. Uphill, downhill, curvy roads and even high winds have never presented an issue. Honestly, it is extremely fun to drive and we did so again this week, with a couple days of mid-week camping.
Although each truck and camper combination will have different specs and characteristics, I also agree with others that suggest running stock, at first, to see if you're satisfied with how the rig handles.
Good luck with your upcoming purchase. Most of all - Be safe and have FUN!