Experience towing w/ 2WD F250, 2500 or other 3/4 ton

It’ll pull the trailer down the road same as a 4x4 and while I personally need 4wd more than some for what we do, sounds like you may not and that’s fine.
Not really sure what else you’re asking. Other than opening a can of worms, lol

But given your perceived lack of experience, based on your initial post, a 4wd may come in handy once in a while