I have no experience with Lance campers HOWEVER, my experience with Toyota Tundra pickups and my Outfitter Apex 8 may help.
I have had my Outfitter Apex 8 on a Tundra since 2004 without issues. I do have load range E tires and Air Lift air bags but that's it as far as mods.
My 2004 Tundra is still going strong at 120,000 miles. I know because I gave it to my son. My 2014 Tundra is a dream with the TC on it's back.
I routinely carry full water and lots of other ****, er, stuff with me plus another human bean. I know I'm over the weight placards of the truck but based on my personal experience, there have been NO ISSUES.
PM me if you want details.