+1 on the Sagulator
http://www.woodbin.com/calcs/sagulator.htm In general, "engineered wood" products (press board, OSB, plywood) are less stiff than solid woods.
One thing to note is that deflection is proportional to the cube (^3) of thickness. So double the thickness, you increase stiffness by a factor of 8.
If you want a good compromise of weight vs. stiffness, consider a shop-built torsion box.
http://www.core77.com/blog/furniture_design/a_look_at_torsion_boxes_26334.asp Or adapt one from a "hollow core" door.