I can't imagine it would be a problem. You'd simply run on the gas engine more than you would in non-tow mode.
But... if saving money is the goal, the hybrid version of the Escape will usually run about USD20K more on a new vehicle. No idea about the Toyota.
You might be better off getting a used gasser with the tow capacity you want. It's going to take a lot of miles to offset that much of a price difference, especially if electricity isn't that much cheaper on a per-mile basis.
- 2019 Grand Design 29TBS (had a Winnebago and 3x Jayco owner)
- 2016 F-150 3.5L MaxTow (had Ram 2500 CTD, Dodge Durango)
- 130W solar and 2005 Honda EU2000i twins that just won't quit