I really don't see why this wouldn't work - but I think it would only work if you stick to paved roads. The tag won't have the clearance, articulation, or tire size to match/complement your drive axle on uneven surfaces. I saw a truck camper a while back that had a tag on it - they're out there. As I think a lot of people with TCs buy them to leave the pavement, I don't see the market. But I'll fully admit that I have tunnel vision here and that's based on my own social bubble.
As said elsewhere in this thread, tire scrub is relied on all the time for tandem trailers and trucks. It looks like it might even run ST tires, which are supposed to be designed to endure more scrub than passenger tires.