I had my truck camper and I loved it and the only reason I sold it was because of my health issue and climbing in the stairs and moving all my photography gear in and out.
I then went to a class c which was amazing but did not fit down the roads that I liked.
I then went to a Ford Transit that I converted myself and I really love it. But a truck camper keeps calling me because having the bed over the cab of the truck frees up so much extra space without adding the unnecessary length to the unit.
I have seriously considered going back to a TCer but I love my van and the ability to move from the driver's seat into the back and vice versa with no hassles is the biggest selling point.
If you're concerned about how it handles then don't go overboard with the weight of your camper. My unit was quite light and it handled amazingly well.
The only real drawback that I had was where I live is very windy and driving down the highway into the wind you could feel the camper catching the wind and lifting. I do not experience that with the van.
If I was to do it again I would get an oversized truck to haul the camper. For instance if the camper said it would fit on a 350 I would get a 450 or a 550. Just to have that extra ability to handle the weight to me as well worth the cost.