I have a 2014 Dodge Ram 1500 4x4 V8 Hemi and I can turn off my truck anti sway option with the push of a button. I have also two older Ram 1500s V8 and a former Ram 2500 V10 4x4 and I can tell you will be most challenged in the high mountains of the Rockies and western USA with that amount and length of trailer.
I do have experience in towing a 28 foot 5000 lb trailer in those mountains and chose to use the 2500 V10 for those chores and safety plus of course an Equalizer WDH. Better safe than sorry. Cheers to the 4 great Rs of life.