Retired out of Temecula. In-laws in Redding. Did the drive at least 2x/year since '77. Trust me on this one. First off. Orange Grove (stayed there many times) is on 58. Use it, as others have said, to access 395. Last time I was through there, in October, K rails, due to road construction, were on the south bound side for miles making for very narrow lanes. If that's a concern, outside of Mojave, take 14 to Palmdale, then go over to 215/15. Either way, get to 15/215. 210 is absolutely not the way to go in an RV. Plus, you will find Tehachapi is a much easier pass than Grapevine to negotiate. Road construction is probably still ongoing on both 215 and 15. But, 15 is a much better choice because it avoids the messy interchanges in Riverside. Now . . . Reference 'Las Vegas to Mission Bay RV Resort' that is currently 2 topics above you. Peruse how to get to MBRVR once you're in the San Diego area. And most important, read what I had to say about traffic from Cajon Pass on. Trust me on this one.