Baltimore to Nashville and back at end October?

Take it that the 25th is arrival date & 3rd is departure date. That leaves 8 days of which one will be picking up & stocking the RV & one will be return day. That leaves 6 full travel days. Not much time. Figure a route of not much more than 1200 miles to have time to do more than drive by attractions. Draw an arc no more than 400 miles from Baltimore. Anything past that is going to be too far. Make your loop route within it.