best roads to travel from Fl to Lawton Ok in RV

Are you going for graduation?

We just drove Tampa-Oklahoma City in a 30' Class A towing a Jeep. No problems on I-10 but did avoid rush hour in Tallahassee, Mobile, Baton Rouge and Lafayette. Bypassed New Orleans area on I-12. Nice drive on I-49 from Lafayette to Shreveport. I-20 was OK, but I-635 Dallas bypass has major construction on north side. Definitely will avoid I-635 next time. Also, we encountered the normal heavy traffic between Dallas and Denton on I-35E. Since Lawton is your destination, you may want to check if highway 281 is your best option (goes north from I-20 to Wichita Falls, Texas, and into Oklahoma).

We had no problems finding gasoline or concerns about height, including the tunnel in downtown Mobile.

We go there every year. We take I-10 to I-49 in LA. I-49 to I-20. About Tyler TX, take I-69 North to Greenville TX then pickup US 380 West to Decatur TX, then I-287 North thru Wichita Falls TX then hop on I-44 to Lawton.

We usually fill up at half a tank so we don't have to worry about finding fuel. Look for truck stops on the interstate highways. We like Flying J, Pilot or Loves. Petro and TA "so-so"
Flying J I-10 exit 192.
Pilot Travel Center I-20 at Tyler TX.
Loves exit I-20 exit 209 Shreveport LA.
Loves Hwy 287 Wichita Falls, TX
Also: Check websites for: Pilot Flying J Travel Centers
TA truck stops
Petro Truck Stops
Loves Truck Stops

Do you need campground recommendations?

The information you folks have sent was very informative. I will check out the travels you advised of. We have some family to see and mother nature is very active. I like the graduation question , we can always have another graduation , the ole farts graduate again. but thanks again.

I-95 - Turnpike - I-75 to I-10
I-10 to Mobile
US-98 to Hattiesburg
US-49 to Jackson
I-20 to 635 loop around Dallas
I-635 to I-35E
I-35E to US-380
US-380 to US-287
US-287 to Wichita Falls
I-44 north to Lawton (toll road)

There are no bridges or overpasses on this route that will be factor for a legal-height motorhome, if you follow truck routes where marked in any towns you go through.

But I know where to find one in Wichita Falls that is too low for some 4x4 pickup trucks. It is on a back street, not a highway or designated route.

They gave you the best routes. We traveled from Panama City to Iowa Park which is 15 miles west of Wichita Falls for the past 25 years. If you want a good campground in Lawton look at Doris campground in the Wichita Mountains. You will not be disappointed.