You can find DEF now at quite a few places. Some truck stops (e.g. Pilot) are selling it at the pump. The tank on my F350 holds 5 gallons. When I check the tank from the Driver's Information Panel, it will give me an indication when it gets to 50% full.
I purchase my DEF at Autozone in 2.5 gallon containers. They have a nozzle for adding it to the truck. I think the price is $14.99+tax. You might be able to find it less expensive, but I go through 2.5 gallons in about 3000 miles, so at $14.99, I'll pay a little more for the convenience. You could buy 2-3 containers, and probably be set for your whole trip.