The cape may/Lewis ferry is a nice break from driving and this will put you en-route to head south on 1/13 through the Delmarva peninsula. Cross the Chesapeake Bay Bridge tunnel (it's been a while but I believe it's a $22 toll). Once your on my side of the water skip past Virginia Beach and head south to the Outter Banks, it's sooooo nice down there. Take US 12 south all the way to The ferry to Ocracoke island. Once on the island spend a night or two at the state park... from there you can catch another ferry to Cedar Island, through Moorehead city and onto 17 towards Myrtle Beach... that's as far as I can take you.
