Easton, PA To Hanover, PA

Thanks for the suggestions. I did go to Google maps and it did use the primary route as suggested by gbopp. The reason I am asking here is actually for first hand knowledge of the route which gbopp stated he has. I have used GM in the past and it seems not to know how many stop lights there are on secondary roads AND how likely you are to catch them.

Use Google Maps but it can change because it takes traffic in to consideration so 2 days before you leave could be a different route than when your actually on your way if there is lets say an accident or road work.

Go on Google Maps, enter your start and destination.
It will probably tell you I-78 to I-81 to I-83 to US 15 to PA 94.
I think it's the easiest and best route. I have traveled it many, many times.