If you have it on your dash it shouldn't be a problem. I often times set up locations in my house and my desk is several feet from the window and I still get satellite reception. Not familiar enough with that model to answer about programming a route but reading it does say it has a multi-point route planner. I do something similar when I am traveling long distance and want to take a route different than default; I will select way-points along the route I want and then travel to each of those. Newer model may make it easier.
Don