Houston, TX Best way through(west to east)

Thanks to all who've replied and offered much good advice. Only drove thru Houston once on I-10 and recall there were a couple of spots where it seemed easy to make a wrong turn because of not being in the correct lane. We usually try to drive in the right-hand lane, or the second lane in from the right, in any of the big cities that have heavy traffic congestion.
Is this a good strategy when traversing Houston?

Thanks,
Jim