Even though we may pay 5-15 cents more per gallon, we prefer to stop at truck stops to get fuel, potty, and food/snacks. I hate one hole bathrooms and two pump gas stations. The wife and I (68) do stop every 2 hours to stretch but generally for only 5 minutes not 10, unless it is also a fuel/pee stop. Going via CA adds about 800 miles to your drive or another 12+ hours of driving even at freeway speed.
On the first day I do not mind 14-16 hour drive days but then I like a 10 hour next day with a good meal and restful nights sleep. We bring our own pillows just to help ensure the restful sleep. I will also use a sleep aid if I am having trouble winding down from the days drive. Then I will be ready for another 14-16 hours.