I-10 in Baton Rouge can be very bad. Don't get there during or close to rush hours.
I-10 also has the Atchafalaya Bridge which is long and a little rough but the main concern is if they have a wreck, you will be stuck for a long time or a long detour. Watch the traffic reports.
I-20 is bad in Shreveport. Use the loop.
I-20 has a lot of washboard areas but not too bad.
I-20 There was construction around the Texas/La line back in June. Do not know if completed or not.