Jacksonville FL to Pigeon Forge TN to Evansville IN

If possible, try to limit yourself to 4 or 5 hours a day driving. Yes most folks can do more, but to make the trip less stressful 5 hours is a nice easy number. The interstate route of 530 miles is an easy 2 day run. 95 to 26 to 40 to 411 .
As to mountains, are you pulling a toad? Interstates tend to have fewer really steep sections than secondary roads, but are also less interesting as far as things to see and do.

Generally using the interstate roads will be the best. Each leg could be 1 day, but I would take 2 days. Maybe more if stopping at interesting areas to explore.

Perhaps Google the route and see what's of interest along the route.

BTW You're in the wrong forum. Click on Notify Moderator and request a change to Roads and Routes. :)

OP would help by letting us know what type of RV. We use 40, 26, & 95 regularly between IN and the East coast of FL to avoid 75 through GA (and of course Atlanta.) We're towing a fifth wheel with a diesel pickup. "Safest" is tough to describe, but I think our route is safer than 75. You must be ready for long grades in NC and TN and turns on 40 through the mountains. We have taken 26 through Johnson City to avoid construction on 40--from memory it has some long steep grades. You've got to be comfortable driving the RV on these roads. Definitely stick to Interstates through NC and eastern TN.

Hendersonville NC good place to stop. Lot of stuff to see in that general area. Asheville is more touristy. You should stop at Bushes Beans on 411, plenty of parking and good food.

Sorry about that, I notified the moderator. We will not be pulling a car btw.

Moved to Roads and Routes

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