Long grades in the Appalachian's

All the Interstates in the East are easy to handle with common sense driving. Tow haul mode works great if you have it. Slowing down by pumping the brakes and then manually downshifting at the slower speed does the same thing. Don't ride your breaks going downhill, simply pump them if necessary. I prefer the free ride downhill to the fuel burning climb uphill. Having crisscrossed the Rockies many times the only real difference is that the ups and downs are more frequent and last longer. In the East they can be just as steep but tend to be much shorter. I26, 40, 77, and 64 are all easily handled with any RV that is driven properly (at a speed suitable for conditions). Stay in the right lane, let the fast traffic go by, take your time and enjoy the scenery. 26, 40 and 77 all have some lovely scenery. Use your gearing and tap your brakes now and them, no big deal. If you cross on local roads instead of the Interstate, there are some horrible steep twisting roads that make life more thrilling. I have used some of them in a car or my Class B, but best to avoid them.