We did the Inside Passage by ferry several years ago...without a vehicle. Flew into Juneau and went from there. There really wasn't a town we visited that couldn't be negotiated without having a car. We did use public transportation a couple of times (in Juneau and in Ketchikan), but for the most part we used two footed propulsion. We ate like hogs and came home from that trip a couple of pounds lighter than when we started. And we got to see everything we went up there to see. We much preferred the flexibility of the ferry system, as we watched the "cruisers" get off the ships en masse, barrel through the shore stops and then get back on board without actually having seen Alaska.
The trip was a wander down memory lane, as my Dad lived there before WWII and we followed his photo album through the trip. I even had my picture taken in Sitka, sitting on the same rock he sat on for his picture.
The only driving trip made was a very fast drive up from Idaho to the Kenai so we could help a friend build a house. Next time we will take the TT and take our time.