I've driven from Cincinnati to Florida several times, in a Class C pulling a Jeep toad. As you all know, the right lane exits and a new lane opens all the way to the left. Nobody wants to drive behind a MH, so they speed up to close the gap. Not fun. So one year I planned it to go thru Atlanta at 3 AM. Traffic was light until I ran into a traffic jam. When I was almost through, I went past the problem. Some guy had been in the jam for so long, he fell asleep in the left lane. No horns. Everyone just waited until they could merge and went on their way.
Now I go through Alabama to Pensacola, FL. and then head east to I-75. It doesn't save any time, but my blood pressure remains stable.