U.S. Route 50 America's loneliest route

Don't miss Great Basin National Park right near the Utah/ Nevada border.

BTW - once your get to Utah, it's about 100 miles before you get to anything at Delta. Great view of the dry lakes though.

We have driven most of US-50 through the plains states and many sections in the East and West. Here are a couple of other links that I think might help you plan a trip: Coast to Coast on US-50, US-50 Driving Route.

Middlegate Station in a fun place to hit on a weekend when impromptu jam sessions usually break out. They have a very limited number of RV hookups, many taken by people living there but you can dry camp for free if they have no vacancies. They have a Facebook page that will give you the flavor of this cool dive!

https://roadtrippers.com/us/fallon-nv/food-drink/historic-middlegate-station

We've driven it a few times and it's not void of people but yes, it's an easy pleasant drive. Any road you pick in Nevada will be similar. Drive on the top 1/2 of your tank. It's no time to try to shop for good prices.

If you like lonely desert roads (and who doesn't??), Highway 6 from Bishop to Ely is really great. Make sure your iPod is full of good music -- there is almost nothing on the radio and almost no cell service.

I came across this and it got me dreaming and thinking... gotta do it some day.
http://unusualplaces.org/u-s-route-50-americas-loneliest-road/

The 'loneliest road' slogan was and is advertising. And if it was ever really that lonely today it certainly is not. But, it still is a great drive across Nevada and accesses one of the newest National Parks, the Great Basin Nat'l Park. Well worth the visit.

It's a good stretch of highway and a good way to get to, or come from Yosemite. The way the people in California are bailing out tho it may not always be too lonely.

Great highway to see a lot of nothing! Many animals a great views. I am ready to do it again.
Watch your fuel!