Virginia to Grand Island KOA/ Niagra Falls

Where in Virginia are you starting from? If on the Western end, I would go I-77 to US-19 to I-79 to I-90 to I-190 (exit 53) over the Grand Island bridge to the KOA. Regardless of where you start from, you'll have to get on the I-190 and go over the Grand Island bridge to Exit 18A (Grand Island Blvd.) to the campground.