380 between Greenville where you would exit I-30 and McKinney still has construction.
380 through downtown Denton is 'challenging' just go real slow with narrow lanes.
380 between Denton and Decatur is heavy construction.
That said - I've driven it pulling a 30 ft travel trailer in both directions several times.
I live 18 miles south of 380 on the east edge of the metroples - so sometimes it is a better choice headed east. I always use 380 to get to Camping World in Denton, and to get to I-35 headed north or head west out on 287 toward Amarillo.
But the post above is correct - I-20 around the bottom of DFW is the best thru route. I always use it when heading west toward Abilene even though it adds 25 miles to my trip.
When you cross Lake Ray Hubbard, get in the next to right lane, and into the right lane after crossing Belt-Line. Take I-635 South to I-20. Watch the speed. Mesquite is 60 mph.
When you get close to I-20 - be in the left lane. Weird interchange with US-175/I-20.
Watch out for folks on I-20 trying to cross three lanes of traffic in a half mile to get on US-175 toward downtown Dallas.
The rest of the drive is simple with no crazy intersections.
There is a section of construction near the I-35W junction south of FW and west for a few miles. Not bad.
I have driven straight through on I-30 while towing a few times. But I've been here for 27 years - and know which lane to be in for every interchange.