If you cross to US at Laredo and get on I-35, you can follow 35 all the way to Duluth, Mn which is a couple hrs from the Canadian border.
Then US 53 takes you to International Falls, MN which is across from our town.
This puts you almost dead centre of Canada to head east or west.
Oh ya, wife texted with grandson there today, from Florida, and he said the snow banks were so high the road had narrowed to where the garbage truck could not fit down the street..
We head home Apr 1st but don't figure the snow will be gone yet. :S
Safe travels.